What medicine should I use if my triglycerides are high?
High triglycerides are a common dyslipidemia problem, and if left uncontrolled for a long time, it may increase the risk of cardiovascular disease. Recently, there has been a lot of discussion about triglycerides on the entire Internet. The following is a compilation of hot topics and related data in the past 10 days, combined with medical advice, to provide you with scientific medication guidance.
1. Recent hot topics and statistics
| Topic keywords | Search volume (10,000 times/10 days) | main focus |
|---|---|---|
| Normal range of triglycerides | 28.5 | Diagnostic Criteria and Grading |
| How to reduce high triglycerides | 42.3 | Non-pharmacological and pharmacological therapies |
| Triglyceride lowering drug recommendations | 35.7 | Specific drug selection and side effects |
| Chinese medicine for lowering triglycerides | 19.2 | The efficacy and controversy of traditional Chinese medicine |
2. List of commonly used triglyceride-lowering drugs
| drug type | Representative medicine | Mechanism of action | Applicable situations |
|---|---|---|---|
| fibrates | fenofibrate, bezafibrate | Activate PPAR-α receptors to accelerate decomposition | Simple triglycerides were significantly elevated |
| Statins | Atorvastatin, rosuvastatin | Inhibit cholesterol synthesis | People with elevated cholesterol |
| Omega-3 fatty acids | EPA/DHA preparation | Reduce hepatic VLDL secretion | Mild to moderate elevation or adjuvant treatment |
| Niacin | acipimox | Inhibit lipolysis | less preferred |
3. Precautions for drug selection
1.Stratified treatment principles: According to the "Guidelines for the Prevention and Treatment of Dyslipidemia in Adults in China", triglyceride levels >5.6mmol/L require immediate drug intervention, and levels between 2.3-5.6mmol/L require assessment of other risk factors.
2.Risks of combined medication: The combination of fibrates and statins may increase the risk of myopathy, and the CK value needs to be strictly monitored. The "statin + fenofibrate" combination that has been hotly discussed on the Internet recently must be used under the guidance of a doctor.
3.Medication for special populations: Pregnant women are prohibited from taking fibrates. Diabetic patients prefer fenofibrate. Patients with renal insufficiency need to adjust the dose.
4. Hot suggestions for non-drug intervention
| intervention method | Specific measures | Effect estimate |
|---|---|---|
| diet modification | Limit refined sugar, alcohol, and increase dietary fiber | Can be reduced by 15-25% |
| exercise therapy | 150 minutes of aerobic exercise per week | Can be reduced by 20-30% |
| weight management | Control BMI between 18.5-23.9 | Every 5kg can be reduced by 30% |
5. Analysis of recent controversial topics
1.Controversy over the efficacy of traditional Chinese medicine: Although the "red yeast extract" that is hotly discussed on the Internet contains natural statins, the active ingredients are unstable and are not recommended to replace regular drug treatment.
2.Health product risk warning: A popular "fish oil capsule" on an e-commerce platform was exposed to have insufficient DHA content. When choosing Omega-3 preparations, you should look for the drug batch number.
3.Genetic testing boom: The recently popular "blood lipid metabolism gene testing" has certain reference value for drug selection, but it cannot completely replace traditional testing methods.
Summary: Triglyceride-lowering drugs need to be selected individually. It is recommended that patients diagnosed for the first time undergo a fasting blood lipid review and develop a plan based on liver function, kidney function and other indicators. Recent studies have shown that lifestyle intervention combined with drug treatment can increase the effectiveness to more than 80%. Please follow your doctor’s advice when taking specific medications and avoid buying medications recommended online.
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